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| The Garcin Lab | |||
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Dr. D. GARCIN CMU/ Dpt MIMOL Rue Michel-Servet 1 1211 Genève 4 Suisse Dominique.Garcin@unige.ch Tel.: 022 379 56 76 Fax: 022 379 55 02 |
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| Research's subject | Group's publications | Team's members | To Find |
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| Group's publications | |||
| MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors. BMC BIOLOGY 2012 vol. 10 pp. 44-44 CASTANIER C, ZEMIRLI N, PORTIER A, GARCIN D, BIDÈRE N, VAZQUEZ A, ARNOULT D Short double-stranded RNAs with an overhanging 5' ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoys. JOURNAL OF BIOLOGICAL CHEMISTRY 2011 vol. 286(8) pp. 6108-6116 MARQ JB, HAUSMANN S, VEILLARD N, KOLAKOFSKY D, GARCIN D Human parainfluenza virus type 2 L protein regions required for interaction with other viral proteins and mRNA capping. JOURNAL OF VIROLOGY 2011 vol. 85(2) pp. 725-732 NISHIO M, TSURUDOME M, GARCIN D, KOMADA H, ITO M, LE MERCIER P, NOSAKA T, KOLAKOFSKY D Recombinant Sendai viruses expressing fusion proteins with two furin cleavage sites mimic the syncytial and receptor-independent infection properties of respiratory syncytial virus. JOURNAL OF VIROLOGY 2011 vol. 85(6) pp. 2771-2780 RAWLING J, CANO O, GARCIN D, KOLAKOFSKY D, MELERO JA Induction of influenza-specific mucosal immunity by an attenuated recombinant Sendai virus. PLOS ONE 2011 vol. 6(4) pp. 18780- LE TV, MINOROVA E, GARCIN D, COMPANS RW Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway. EMBO REPORTS 2010 vol. 11(2) pp. 133-138 CASTANIER C, GARCIN D, VAZQUEZ A, ARNOULT D Unpaired 5' ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-I. JOURNAL OF BIOLOGICAL CHEMISTRY 2010 vol. 285(24) pp. 18208-18216 MARQ JB, KOLAKOFSKY D, GARCIN D Hepatitis C virus controls interferon production through PKR activation. PLOS ONE 2010 vol. 5(5) pp. 10575-10575 ARNAUD N, DABO S, MAILLARD P, BUDKOWSKA A, KALLIAMPAKOU KI, MAVROMARA P, GARCIN D, HUGON J, GATIGNOL A, AKAZAWA D, WAKITA T, MEURS EF The Double-stranded RNA Binding Domain of the Vaccinia Virus E3L Protein Inhibits Both RNA- and DNA-induced Activation of Interferon beta JOURNAL OF BIOLOGICAL CHEMISTRY 2009 vol. 284(38) pp. 25471-25478 MARQ JB, HAUSMANN S, LUBAN J, KOLAKOFSKY D, GARCIN D Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways. JOURNAL OF BIOLOGICAL CHEMISTRY 2008 vol. 283(46) pp. 31706-31718 HAUSMANN S, ZHENG S, COSTANZO M, BROST RL, GARCIN D, BOONE C, SHUMAN S, SCHWER B RIG-I and dsRNA-induced IFNbeta activation. PLOS ONE 2008 vol. 3(12) pp. 3965-3965 HAUSMANN S, MARQ JB, TAPPAREL C, KOLAKOFSKY D, GARCIN D Activation of the beta interferon promoter by unnatural Sendai virus infection requires RIG-I and is inhibited by viral C proteins. JOURNAL OF VIROLOGY 2007 vol. 81(22) pp. 12227-12237 STRÄHLE L, MARQ JB, BRINI A, HAUSMANN S, KOLAKOFSKY D, GARCIN D Suppression of the Sendai virus M protein through a novel short interfering RNA approach inhibits viral particle production but does not affect viral RNA synthesis JOURNAL OF VIROLOGY 2007 vol. 81(6) pp. 2861-2868 MOTTET-OSMAN G, ISENI F, PELET T, WIZNEROWICZ M, GARCIN D, ROUX L Targeting of the Sendai virus C protein to the plasma membrane via a peptide-only membrane anchor JOURNAL OF VIROLOGY 2007 vol. 81(7) pp. 3187-3197 MARQ JB, BRINI A, KOLAKOFSKY D, GARCIN D Sendai virus budding in the course of an infection does not require Alix and VPS4A host factors VIROLOGY 2007 vol. 365(1) pp. 101-112 GOSSELIN-GRENET AS, MARQ JB, ABRAMI L, GARCIN D, ROUX L Sendai virus RNA polymerase scanning for mRNA start sites at gene junctions VIROLOGY 2007 vol. 362(2) pp. 411-420 PLATTET P, STRAHLE L, LE MERCIER P, HAUSMANN S, GARCIN D, KOLAKOFSKY D Paramyxovirus mRNA editing, the "rule of six" and error catastrophe: a hypothesis JOURNAL OF GENERAL VIROLOGY 2005 vol. 86(Pt 7) pp. 1869-1877 KOLAKOFSKY DANIEL, ROUX LAURENT, GARCIN DOMINIQUE, RUIGROK RWH Identification of Paramyxovirus V protein residues essential for STAT protein degradation and promotion of virus replication JOURNAL OF VIROLOGY 2005 vol. 79 pp. 8591-8601 NISHIO MACHIKO, TSURUDOME MASATO, ITO MORIHIRO, GARCIN DOMINIQUE, KOLAKOFSKY DANIEL, ITO YASUHIKO A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability JOURNAL OF VIROLOGY 2004 vol. 78 pp. 8799-8811 GARCIN DOMINIQUE, MARQ JEAN-BAPTISTE, ISENI FREDERIC, MARTIN STEPHEN, KOLAKOFSKY DANIEL Viral DNA polymerase scanning and the gymnastics of Sendai virus RNA synthesis VIROLOGY 2004 vol. 318 pp. 463-473 KOLAKOFSKY DANIEL, LE MERCIER PHILIPPE, ISENI FREDERIC, GARCIN DOMINIQUE Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis EMBO JOURNAL 2002 vol. 21 pp. 5141-5150 ISENI F, GARCIN D, NISHIO M, NANCY KEDERSHA, PAUL ANDERSON, KOLAKOFSKY D Ambisense sendai viruses are inherently unstable but are useful to study viral RNA synthesis JOURNAL OF VIROLOGY 2002 vol. 76 pp. 5492-5502 LE MERCIER P, GARCIN D, HAUSMANN S, KOLAKOFSKY D Chemical modification of nucleotide bases and mRNA editing depend on hexamer or nucleoprotein phase in Sendai virus nucleocapsids RNA (NEW YORK, N.Y.) 2002 vol. 8 pp. 1056-1067 ISENI F, F. BAUDIN, GARCIN D, MARQ JB, RW. RUIGROK, KOLAKOFSKY D All four Sendai Virus C proteins bind Stat1, but only the larger forms also induce its mono-ubiquitination and degradation VIROLOGY 2002 vol. 295 pp. 256-265 GARCIN D, MARQ JB, STRAHLE L, LE MERCIER P, KOLAKOFSKY D Sendai virus, a murine parainfluenza virus type 1, replicates to a level similar to human PIV1 in the upper and lower respiratory tract of African green monkeys and chimpanzees VIROLOGY 2002 vol. 297 pp. 153-160 MARIO H. SKIADOPOULOS, SONJA R. SURMAN, JEFFREY M. RIGGS, WILLIAM R. ELKINS, MARISA ST. CLAIRE, NISHIO M, GARCIN D, KOLAKOFSKY D, PETER L. COLLINS, BRIAN R. MURPHY The carboxyl segment of the mumps virus V protein associates with Stat proteins in vitro via a tryptophan-rich motif VIROLOGY 2002 vol. 300 pp. 92-99 NISHIO M, GARCIN D, SIMONET V, KOLAKOFSKY D |
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